Sunday, September 25
(location: "Caballus" (old clinic for horses) at campus Bischofsholer Damm 15, Hannover)
| 17:00 |
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22:00 |
Registration |
19:00
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-
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22:00 |
Welcome Reception
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Monday, September 26
(location: Lecture hall of Institute of Pathology at campus Bünteweg 17, Hannover)
| 08:30 |
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Registration |
09:00
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-
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09:15 |
Welcome address by the President of the University of Veterinary Medicine Hannover
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| 09:15 |
- |
10:00 |
Inaugural Lecture
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Alejandro Thiermann: How to safely manage pestivirus during animal production and trade
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Session 1: Basic virology
Chair: Martin Beer, Heinz-Jürgen Thiel
| 10:00 |
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10:45 |
Keynote Lecture
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Norbert Tautz: Recent advances in the molecular biology of pestiviruses |
| 10:45 |
- |
11:15 |
Coffee break
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| 11:15 |
- |
12:30 |
Oral Presentations |
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Kay Choi: Structure-based mechanism of autoproteolysis and interferon subversion by pestivirus Npro (oral ID 01) |
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Thomas Krey: Crystal structures of the pestivirus envelope glycoprotein Erns in complex with potential substrates reveal similarities to the catalytic mechanism of other T2-RNases (oral ID 02) |
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M. Alejandro Tortorici: Pestiviral polyprotein processing revealed by the crystal structure of the Classical Swine Fever virus protease-helicase (oral ID 03) |
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Stefanie Schmeiser: Electron tomography reveals new insights into pestiviral morphogenesis (oral ID 04) |
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Martin Beer: A recombinant BVDV expressing a stable E2-NS2 fusion protein is characterized by incomplete budding processes into the rER and allows unique ultra-structural analyses (oral ID 05) |
12:30
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-
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14:00 |
Lunch
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| 14:00 |
- |
14:45 |
Oral Presentations |
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Sophia Christin Austermann-Busch: Influence of RNA secondary structure and terminal phosphates and hydroxyls of RNA molecules on RNA recombination of pestiviruses (oral ID 06) |
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Oliver Klemens: Two amino acid exchanges are sufficient to restore pestivirus morphogenesis in the absence of uncleaved NS2-3 (oral ID 07) |
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Benjamin Lamp: An internal cleavage within NS3 of Classical Swine Fever virus (CSFV) generates a proteolytically active protease fragment (oral ID 08) |
| 14:45 |
- |
17:00 |
Poster Session |
| 19:00 |
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Congress dinner at the Restaurant "Gartensaal" of the New Town Hall, Trammplatz 2, Hannover |
Tuesday, September 27
(location: Lecture hall of Institute of Pathology at campus Bünteweg 17, Hannover)
Session 2: Evolution, epidemiology and control
Chair: Ernst Peterhans, Stefan Vilcek
| 09:00 |
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09:45 |
Irene Greiser-Wilke Keynote Lecture
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Julia Ridpath: Sorting out pestiviral phylogeny: A tale of viral swarms, red herrings and sons of B's |
| 09:45 |
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10:30 |
Oral presentations
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Claudia Bachofen: Five calves persistently infected with Border Disease virus (BDV) detected in Switzerland (oral ID 09) |
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Alexander Postel: Genetic and antigenic characterization of a novel sheep pestivirus most closely related to CSFV (oral ID 10) |
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Helen Crooke: How much CSFV does a pig need to eat to become infected? (oral ID 11) |
| 10:30 |
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11:00 |
Coffee break
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11:00
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-
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12:00 |
Oral presentations
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Sandra Blome: Undetected long-term persistence of moderately virulent Classical Swine Fever virus in a wild boar population? (oral ID 12) |
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Christoph Staubach: Database for monitoring Classical Swine Fever (CSF) in wild boar in the EU (oral ID 13) |
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Elena Di Labio: Critical success factors for rapid BVD-control at country level: reduction of PI-prevalence in newborns by 95 % in less than three years (oral ID 14) |
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M. Daniel Givens: Detection of cattle persistently infected with Bovine Viral Diarrhea virus using a non-invasive, novel testing method (oral ID 15) |
| 12:00 |
- |
12:15 |
"Poster prize" session
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| 12:15 |
- |
13:45 |
Lunch
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Session 3: Virus-host interactions
Chair: Manuel Borca, Joe Brownlie
| 13:45 |
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14:30 |
Keynote Lecture
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Nicolas Ruggli: Molecular immunopathogenesis of Classical Swine Fever virus infections |
| 14:30 |
- |
15:30 |
Oral presentations
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Tomokazu Tamura: Acquisition of pathogenicity by serial passages of a live attenuated vaccine strain of Classical Swine Fever virus in pigs (oral ID 16) |
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Yoshihiro Sakoda: Enhancement of pathogenicity in pigs by the mutation of N136D in Npro of Classical Swine Fever virus by suppressing type I interferon induction (oral ID 17) |
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Christiane Riedel: CSFV core protein is important for the infection of IFN-primed cells (oral ID 18) |
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Christoph Zürcher: Pestiviral Erns: The need for yet another RNase (oral ID 19) |
| 15:30 |
- |
16:00 |
Coffee break
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16:00
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-
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16:45 |
Oral presentations
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Simon Graham: Interaction of Classical Swine Fever virus with porcine blood dendritic cells (oral ID 20) |
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Llilianne Ganges: Upregulation of CD4, CD8 T lymphocytes modulates the immunopathogenesis of a mild clinical CSF in domestic pigs (oral ID 21) |
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Deborah Finlaison: Clinical effects of experimental Bungowannah virus infections in weaner pigs and pregnant sows (oral ID 22) |
| 16:45 |
- |
18:00 |
"Workshop on immunopathology of Classical Swine Fever" hosted by National Veterinary Institute, Technical University of Denmark (DTU)
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Chair: Ase Uttenthal
Introduction: Jens Nielsen
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Plenum debate:
Initially adressing the question "Is the immune system a double-edge sword in CSFV-infections?", the workshop will create an informal forum to discuss the challenges of recent and future research on immunopathological aspects of classical swine fever. All interested delegates are invited to participate in the debate.
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Wednesday, September 28
(location: Lecture hall of Institute of Pathology at campus Bünteweg 17, Hannover)
Session 4: Biologicals and diagnostics
Chair: Martin Hofmann, Frank Koenen
| 09:00 |
- |
09:45 |
Keynote Lecture
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Gregor Meyers: Basic research paves the way to novel safe and effective pestivirus vaccines |
| 09:45 |
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10:30 |
Oral presentations
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Patricia Renson: CP7_E2alf oral vaccination attenuates pathogeny two days before a challenge with a moderately virulent CSFV strain with close potency to C-strain (oral ID 23) |
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Denise Meyer: New insights into the antigenic structure of the Classical Swine Fever virus glycoprotein Erns (oral ID 24) |
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Fabian Deutskens: Identification of an antigen in a BVD-vaccine inducing alloantibodies linked to bovine neonatal pancytopenia (oral ID 25) |
| 10:30 |
- |
11:00 |
Coffee break
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11:00
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-
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11:45 |
Oral presentations
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Peter Kirkland: Detection of BVDV antigens in hair samples from alpaca, deer and cattle (oral ID 26) |
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Melissa Batonick: Engineering an improved Classical Swine Fever ELISA to detect antibody in sera (oral ID 27) |
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Jean-Baptiste Hanon: A field study in Belgium to compare performances of two BVD-V diagnostic tests to detect PI animals (oral ID 28) |
| 11:45 |
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12:30 |
Scientific conclusions (Summary with all Chairmen)
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Close of conference
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| 12:45 |
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Lunch |
Programme
